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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Mol Cancer Ther. 2008 Nov;7(11):3586–3597. doi: 10.1158/1535-7163.MCT-08-0653

Figure 1. cDNA sequence of human EGFR and EGFRvIII and the design of anti-EGFRvIII siRNA.

Figure 1

A, cDNA sequence of wild-type EGFR: the sequence corresponding to the deletion resulting in generation of the EGFRvIII is highlighted in yellow. B, cDNA sequence of EGFRvIII: the junction point generated by the deletion highlighted in A and the sequence used for the design of anti-EGFRvIII siRNA is boxed in red.