Fig 1.
Serum alanine transaminase (ALT) levels in wild-type and Nrf2-null mice (n=5) pretreated with vehicle (DMSO) or CDDO-Im and then administered acetaminophen. ALT concentrations are expressed as International Units/Liter. Values are expressed as mean ± S.E.M. ALT values were log transformed before statistical analysis. Asterisks (*) indicate a statistically significant difference from DMSO pretreated wild-type mice (p ≤ 0.05).