Fig 2.
GSH, GSSG, and total GSH concentrations in livers from wild-type and Nrf2-null mice pretreated with vehicle or CDDO-Im (1 mg/kg, i.p.) and then administered acetaminophen (500 mg/kg, i.p.). Livers were removed 6 h after acetaminophen administration. Data is expressed as relative to control mean ± S.E.M. Asterisks (*) indicate statistically significant differences between CDDO-Im treated and control groups (p ≤ 0.05).