TABLE 2.
Regional distribution of Angiotensin II AT1A and AT1B receptor subtype mRNA in the lower lumbar (L4–L5) spinal cord segments
| Grey Matter | White Matter | ||||||
|---|---|---|---|---|---|---|---|
| Spinal Cord Segment | Receptor Subtype | Superficial dorsal horn | Lamina X | Ventral horn | Dorsal funiculus | Lateral funiculus | Ventral funiculus |
| nCi/g | |||||||
| L4 segment | AT1A | 41.1 ± 1.9 | 47.4 ± 2.8 | 41.3 ± 1.9 | 6.5 ± 0.6 | 5.6 ± 0.4 | 5.6 ± 0.4 |
| AT1B | 19.8 ± 2.3 | 18.8 ± 1.4 | 20.4 ± 1.9 | 5.0 ± 1.1 | 3.3 ± 0.6 | 4.0 ± 0.7 | |
| L5 segment | AT1A | 49.7 ± 3.8 | 64.7 ± 6.3 | 51.8 ± 3.5 | 6.5 ± 0.7 | 5.2 ± 0.8 | 6.4 ± 0.9 |
| AT1B | 15.8 ± 0.5 | 18.2 ± 0.4 | 18.1 ± 1.7 | 6.1 ± 0.2 | 5.8 ± 0.3 | 6.0 ± 0.2 | |
Values are means ± SEM from group of five animals, measured individually as described under Materials and Methods, and are expressed as nCi/g tissue equivalent.