Figure 3.

Quantification of neuronal cell cycle activity within cortical layers. Percentages of neurons exhibiting immunoreactivity for cell cycle re-entry were tabulated in both male and female B6-R1.40 transgenic and non-transgenic mice aged 6–12 months. A–C, Cell cycle re-entry was tabulated by scoring cyclin A (A) and cyclin D (B) immunoreactive neurons and polyploid neurons (C) in the frontal cortex.