. Author manuscript; available in PMC: 2009 May 11.

Published in final edited form as: Science. 2008 Oct 10;322(5899):268–271. doi: 10.1126/science.1164164

Table 1. Pfn^−/− & GrB^−/− gB-CD8 are less efficient than WT gB-CD8 at inhibiting HSV-1 reactivation in a common pool of latently infected neurons.

HSV-1 reactivation detected by plaque assay of supernatants from dispersed 34–44 dpi WT TG depleted of endogenous CD8⁺ T cells and cultured at one-fifth TG per well with the indicated number and type of gB-CD8 from culture initiation. +, reactivation detected; −, no reactivation detected; X, condition not tested. Data pooled from four independent experiments (n=15–35 cultures per condition).

# gB-CD8 per well	Type of gB-CD8

	WT	Pfn^−/−	GrB^−/−
2×10³	+	×	×
2×10⁴	−	+	+
4×10⁴	−	+	+
5×10⁴	−	+	−
1×10⁵	−	+	−

Table 1. Pfn−/− & GrB−/− gB-CD8 are less efficient than WT gB-CD8 at inhibiting HSV-1 reactivation in a common pool of latently infected neurons.

Table 1. Pfn^−/− & GrB^−/− gB-CD8 are less efficient than WT gB-CD8 at inhibiting HSV-1 reactivation in a common pool of latently infected neurons.