Figure 1.
Exposure of mice to T. regenti causes the production of cercarial-specific IgM, IgG1 and IgG2b antibodies. IgM (a), IgG1 (b), and IgG2b (c) antibodies against T. regenti cercarial homogenate (TrH) in the sera of mice exposed to 1–4 infections. The binding of antibodies to carbohydrate structures was determined following treatment of TrH with sodium periodate (--); versus control mock-treated antigen (-
-). Data points are the mean ± SEM for five mice. Statistical significances (*P < 0.05; **P < 0·01; ***P < 0·001) are relative to naïve mice (day 0).