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. 2008 Nov;30(11-12):585–595. doi: 10.1111/j.1365-3024.2008.01059.x

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Journal compilation © 2008 Blackwell Publishing Ltd

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2·5, which does not permit commercial exploitation.

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T. regenti cercarial homogenate and E/S products dose-dependently trigger IL-4 release from human basophils. Basophils stimulated with various concentrations of TrH (a) and TrE/S antigen (b) release IL-4 in a dose-dependent manner. All stimulations were performed in the presence of IL-3 (2·5 ng/mL). Stimulation of basophils with IL-3 and anti-IgE was performed as negative and positive control, respectively. Statistical significance related to negative control (IL-3): *P < 0·05; **P < 0·01; ***P < 0·001.