Table 1. Cohesin associated to the +/− 1-kb vicinities of TSSs among three different groups of genes in control and CdLS LCLs.
Group | Expression Status in LCLs | Genes with Binding Sites Present at±1-kb Region Surrounding TSS | |||
Control Cells | CdLS Cells (FDR<0.05) | Unique RefSeq Genes (15,162 in Total) | Control Cells (792 in Total) | CdLS Cells (448 in Total) | |
A | No | No | 4,784 | 126 | 72 |
B | Yes | No (FDR>0.05) | 9,199 | 559 | 323 |
C | Yes | Yes (FDR<0.05) | 1,179 | 107 | 53 |
Group A is not transcribed in LCLs, groups B and C are transcribed in LCLs, whereas group C is differentially expressed in CdLS (FDR<0.05).