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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Hypertension. 2008 Nov 3;52(6):1134–1141. doi: 10.1161/HYPERTENSIONAHA.108.121582

Fig. 5.

Fig. 5

Effect of intravenous administration of the Tat fusion proteins on the association of Pyk2 with components of PI3-kinase. Following immunoprecipitation of Pyk2 from lysates of aortic tissue and isolated glomeruli of rats on both diets, the pelleted samples were separated using SDS-PAGE and probed for p110α and p85. Intravenous administration of Tat-AP and Tat-PBM, but not Tat-GBM, disrupted the association of Pyk2 with p110α and p85 in samples obtained from rats on the 8.0% NaCl diet, but did not alter binding to Pyk2 in lysates from rats on the 0.3% NaCl diet. Each lane represents data from a single rat (n = 3 rats in each group).