Table 3.

The S/N ratios from the D-optimal experimental design run order for the multivariate optimization of sheath liquid parameters

Run	Experimental parameters		Experimental responses
	HOAc (%, v/v)	MeOH/H2O (%, v/v)	Signal-to-noise
			N1	N2	N3	N4	L1	L2	L3	L4
1	1.25	98	69	59	50	49	15	13	11	10
2	0.875	78.5	129	109	112	108	41	39	31	30
3	0.5	20	149	112	101	102	57	51	43	41
4	1.625	78.5	44	36	34	35	15	15	10	12
5	2	20	184	197	142	142	74	66	53	54
6	0.5	20	150	110	100	101	56	50	42	40
7	0.5	98	94	89	76	82	24	21	14	19
8	2	20	183	195	142	142	72	67	53	52
9	2	59	64	57	55	51	25	23	18	18
10	0.5	98	90	89	77	83	24	21	16	17
11	0.5	59	32	29	26	27	14	12	10	10
12	1.25	20	96	77	70	73	31	27	21	26
13	2	59	65	59	56	51	24	21	17	17
14	1.25	39.5	90	86	72	76	37	29	25	25