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. Author manuscript; available in PMC: 2009 May 11.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Nov 1;875(1):304–316. doi: 10.1016/j.jchromb.2008.06.028

Table 4.

The S/N ratios from the D-optimal experimental design run order for the multivariate optimization of spray chamber parameters

Run Experimental Parameters
Experimental responses
Drying gas flow rate (L/min) Drying gas temperature (°C) Nebulizer pressure (psi) Signal-to-noise
N1 N2 N3 N4 L1 L2 L3 L4
1 6 220 5 768 574 616 589 101 98 77 73
2 3 120 2 436 378 355 313 102 90 68 63
3 4.5 120 2 591 500 276 437 148 128 105 98
4 3 220 5 695 584 563 507 131 120 95 86
5 3.8 145 4 812 528 636 615 168 138 116 114
6 6 170 2 435 372 225 335 98 87 67 62
7 3 220 5 694 583 560 502 129 121 94 84
8 4.5 220 4 1270 1105 1062 988 271 245 199 185
9 3 120 5 1256 1131 1052 975 258 252 206 194
10 6 120 5 415 293 421 404 115 103 72 82
11 3 220 2 658 528 514 473 131 84 100 103
12 6 220 5 766 570 614 584 97 101 80 71
13 6 220 2 86 79 68 58 12 11 9 8
14 3 170 2 169 183 169 172 44 41 30 31
15 6 120 5 410 289 417 400 114 102 69 77
16 6 170 4 369 324 296 270 77 79 60 63
17 4.5 170 5 90 87 80 86 26 22 16 16
18 6 120 2 81 40.8 60 67 19 17 14 14
19 3 120 5 1260 1128 1054 972 260 249 203 190
20 4.5 170 5 86 92 78 80 23 21 15 17