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. Author manuscript; available in PMC: 2010 Jun 16.
Published in final edited form as: Neuroscience. 2009 Mar 19;161(1):301–310. doi: 10.1016/j.neuroscience.2009.03.020

Figure 6.

Figure 6

Effects of systemic administration of diazepam (10 mg/kg, i.m.), phenobarbital (40 mg/kg, i.p.), and valproate (300 mg/kg, i.p.) on the behavioral seizure score increased by i.c.v. morphine 100 μg or i.c.v. DAMGO 1.5 μg. Diazepam was administered 15 min before administration of morphine or DAMGO. Phenobarbital or valproate was administered 1 h before administration of morphine or DAMGO. Each animal was scored according to the highest class of behavioral manifestation observed during the 1 h observation period. Each value represents mean ± S.E.M. (n=6).**, P<0.01 compared with the Veh+Veh condition; #, P<0.05 compared with Veh+(morphine or DAMGO).