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p53 knockdown primary human fibroblasts have reduced levels of p53R2 and h-mtTFA. Cells expressing scrambled control (scr) or p53 shRNA (p53) analyzed for A. steady-state levels of p53R2 and h-mtTFA by Western blot (actin is shown as a loading control); and B. relative mRNA transcript levels of p53R2 and mtTFA normalized to actin message.
