Figure 8. Effect of CXCL12 administration into the core of the nucleus accumbens on ambulatory activity and stereotypy.
. Administration of CXCL12 (25 ng/0.5 μl) into the core of the nucleus accumbens 15 minutes prior to cocaine (20 mg/kg IP) did not significantly alter A) ambulatory activity or B) stereotypy as compared to the cocaine alone. Data are expressed as mean ± SEM beam breaks/five minute period. N= 8 – 9 per group as indicated for each. (CXCL12/COC vs. SAL/COC; p>0.05)