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. Author manuscript; available in PMC: 2009 May 12.
Published in final edited form as: Ann Neurol. 2009 Apr;65(4):414–423. doi: 10.1002/ana.21591

Table 5. Regions of gray matter loss in MCI subgroups vs. Controls.

Voxel coordinates represent the peak voxel in local maxima, coordinates are expressed in Montreal Neurological Institute stereotactic space.

Regions of gray matter atrophy in dMCI and aMCI patients compared to controls
Brain Region x y z t Statistic z Value
dMCI > Controls
Left dorsolateral prefrontal cortex −44 10 50 3.76 3.61
Left dorsomedial prefrontal cortex −20 −4 64 3.73 3.59*
aMCI > Controls
Left hippocampus −38 −26 −14 4.02 3.84
Right hippocampus 40 −22 −18 3.98 3.81
Right posterior cingulate gyrus 6 −16 38 4.39 4.16
12 −28 38 4.2 4
8 −4 38 4.19 3.99
Right inferior parietal lobe 38 −54 40 4.23 4.03

p<0.05, FWE-corrected;

*

indicates p=0.05, FWE-corrected.