Table 5. Regions of gray matter loss in MCI subgroups vs. Controls.
Voxel coordinates represent the peak voxel in local maxima, coordinates are expressed in Montreal Neurological Institute stereotactic space.
| Regions of gray matter atrophy in dMCI and aMCI patients compared to controls | |||||
|---|---|---|---|---|---|
| Brain Region | x | y | z | t Statistic | z Value |
| dMCI > Controls | |||||
| Left dorsolateral prefrontal cortex | −44 | 10 | 50 | 3.76 | 3.61 |
| Left dorsomedial prefrontal cortex | −20 | −4 | 64 | 3.73 | 3.59* |
| aMCI > Controls | |||||
| Left hippocampus | −38 | −26 | −14 | 4.02 | 3.84 |
| Right hippocampus | 40 | −22 | −18 | 3.98 | 3.81 |
| Right posterior cingulate gyrus | 6 | −16 | 38 | 4.39 | 4.16 |
| 12 | −28 | 38 | 4.2 | 4 | |
| 8 | −4 | 38 | 4.19 | 3.99 | |
| Right inferior parietal lobe | 38 | −54 | 40 | 4.23 | 4.03 |
p<0.05, FWE-corrected;
indicates p=0.05, FWE-corrected.