Table 5. Regions of gray matter loss in MCI subgroups vs. Controls.
Voxel coordinates represent the peak voxel in local maxima, coordinates are expressed in Montreal Neurological Institute stereotactic space.
Regions of gray matter atrophy in dMCI and aMCI patients compared to controls | |||||
---|---|---|---|---|---|
Brain Region | x | y | z | t Statistic | z Value |
dMCI > Controls | |||||
Left dorsolateral prefrontal cortex | −44 | 10 | 50 | 3.76 | 3.61 |
Left dorsomedial prefrontal cortex | −20 | −4 | 64 | 3.73 | 3.59* |
aMCI > Controls | |||||
Left hippocampus | −38 | −26 | −14 | 4.02 | 3.84 |
Right hippocampus | 40 | −22 | −18 | 3.98 | 3.81 |
Right posterior cingulate gyrus | 6 | −16 | 38 | 4.39 | 4.16 |
12 | −28 | 38 | 4.2 | 4 | |
8 | −4 | 38 | 4.19 | 3.99 | |
Right inferior parietal lobe | 38 | −54 | 40 | 4.23 | 4.03 |
p<0.05, FWE-corrected;
indicates p=0.05, FWE-corrected.