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Mean prediction errors over the entire simulation time ranges
| Tissue | Pure Matrine (15 mg/kg) | ACAPHA (0.38 g/kg) | ACAPHA (3.8 g/kg)a |
|---|---|---|---|
| Adipose | -19.0 | -42.4 | -14.5 |
| Kidney | -0.7 | -39.9 | 6.5 |
| Spleen | -59.9b | -13.9 | -11.7 |
| Liver | -34.6 | -33.8 | -25.5 |
| Brain | -28.6 | -10.8 | -31.6 |
| Heart | -36.6 | 30.4 | -45.3 |
| Plasma | -1.5 | 16.5 | -21.6 |
| Muscle | -7.2 | 8.7 | 26.9 |
| Lung | -57.0b | -35.2 | -14.9 |
Matrine equivalent dose was 15 mg/kg.
Mean prediction error absolute value >50%.
