Figure 1. NO·–sensitivity of S. Typhimurium Base Excision Repair mutants.

(A) Growth of S. Typhimurium 14028s and mutant derivatives after the addition of NO· from 2 mM SperNO (at arrow). (B) Survival of Wild Type and xth nfo after exposure to 1 mM SperNO. (C) Rescue of xth nfo cells by additional inactivation of indicated glycosylases after 2 hr exposure to 1 mM SperNO. Asterisks represent statistical significance. (p<0.05.)