Table 2. Functional classes in M. extorquens AM1 and DM4 replicons a.
| Class - Description | Strain AM1 | Strain AM1 | Strain AM1 | Strain AM1 | Strain AM1 | Strain AM1 | Strain AM1 | Strain DM4 | Strain DM4 | Strain DM4 | Strain DM4 | Strain DM4 |
| Chrom. | megaplasmid | p1 | p2 | p3 | Class (%) | Proc. (%) a | chrom. | p1 | p2 | Class (%) | Proc. (%) a | |
| D - Cell cycle control, cell division, chromosome partitioning | 34 | 7 | 1 | 1 | 1 | 0.66 | 16.28 | 38 | 3 | 2 | 0.72 | 17.48 |
| M - Cell wall/membrane/envelope biogenesis | 240 | 30 | 1 | 1 | 4.08 | 245 | 4 | 4.18 | ||||
| N - Cell motility | 126 | 16 | 3 | 2.18 | 121 | 1 | 2.05 | |||||
| O - Posttranslational modification, protein turnover, chaperones | 164 | 32 | 2 | 2.97 | 201 | 2 | 3.41 | |||||
| T - Signal transduction mechanisms | 266 | 34 | 1 | 1 | 4.53 | 304 | 1 | 1 | 5.14 | |||
| U - Intracellular trafficking, secretion, and vesicular transport | 35 | 8 | 1 | 0.66 | 32 | 3 | 0.59 | |||||
| V - Defense mechanisms | 66 | 13 | 1 | 1.20 | 80 | 2 | 1.38 | . | ||||
| B - Chromatin structure and dynamics | 3 | 0.05 | 14.12 | 4 | 0.07 | 13.28 | ||||||
| J - Translation, ribosomal structure and biogenesis | 188 | 14 | 1 | 3.05 | 199 | 1 | 3.36 | |||||
| K - Transcription | 205 | 46 | 2 | 2 | 2 | 3.86 | 243 | 5 | 2 | 4.20 | ||
| L - Replication, recombination and repair | 292 | 161 | 11 | 11 | 3 | 7.17 | 290 | 39 | 7 | 5.65 | ||
| C - Energy production and conversion | 262 | 26 | 1 | 4.34 | 24.50 | 303 | 3 | 2 | 5.18 | 27.39 | ||
| E - Amino acid transport and metabolism | 423 | 31 | 1 | 1 | 6.84 | 468 | 12 | 8.07 | ||||
| F - Nucleotide transport and metabolism | 79 | 11 | 1.35 | 80 | 1.34 | |||||||
| G - Carbohydrate transport and metabolism | 141 | 9 | 2.25 | 144 | 1 | 2.44 | ||||||
| H - Coenzyme transport and metabolism | 124 | 7 | 1 | 1.98 | 123 | 1 | 2.08 | |||||
| I - Lipid transport and metabolism | 164 | 11 | 2.63 | 174 | 2 | 2 | 2.99 | |||||
| P - Inorganic ion transport and metabolism | 200 | 35 | 3 | 1 | 3.59 | 220 | 2 | 3.73 | ||||
| Q - Secondary metabolites biosynthesis, transport and catabolism | 89 | 12 | 1 | 1.53 | 92 | 1 | 1.56 | |||||
| R - General function prediction only | 355 | 40 | 2 | 5.96 | 11.24 | 388 | 1 | 2 | 6.57 | 12.12 | ||
| S - Function unknown | 312 | 35 | 2 | 3 | 5.28 | 327 | 2 | 1 | 5.55 | |||
| CDS with at least one COG hit | 3768 | 578 | 30 | 22 | 10 | 4408 | 66.15 | 4076 | 84 | 21 | 4181 | 70.27 |
| Total CDS | 5227 | 1311 | 46 | 45 | 35 | 6664 | 5772 | 137 | 41 | 5950 |
a
Only the first COG hit of each CDS is considered (CDS may be associated with several COGs).
b
Processes: Cellular processes and signaling (D,M,N,O,T,U,V); information storage and processing (B,J,K,L); metabolism (C,E,F,G,H,I,P,Q); and poorly characterized (R,S).