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. Author manuscript; available in PMC: 2009 May 12.
Published in final edited form as: Immunobiology. 2006 Dec 11;212(4-5):313–323. doi: 10.1016/j.imbio.2006.10.003

Table 1.

C1 inhibitor-mediated modulation of inflammatory disease.

Animal Models Human Disease

Ischemia-reperfusion injury (myocardial, brain, skeletal muscle) Myocardial infarction
Vascular leak associated with thermal injury Capillary leak associated with IL-2 therapy
Gram negative bacterial sepsis and endotoxin shock Sepsis
Hyperacute transplant rejection Cardiopulmonary bypass
Traumatic and hemorrhagic shock
HHS Vulnerability Disclosure