Table 1.
C1 inhibitor-mediated modulation of inflammatory disease.
Animal Models | Human Disease |
---|---|
Ischemia-reperfusion injury (myocardial, brain, skeletal muscle) | Myocardial infarction |
Vascular leak associated with thermal injury | Capillary leak associated with IL-2 therapy |
Gram negative bacterial sepsis and endotoxin shock | Sepsis |
Hyperacute transplant rejection | Cardiopulmonary bypass |
Traumatic and hemorrhagic shock |