Figure 4. Thymocytes in swine or human thymus grafts implanted as single or double grafts.
A) Total thymocyte numbers. Swine or human thymus grafts, transplanted with human fetal liver and human CD34 positive cells injected i.v., were harvested and thymocytes were counted 20 weeks after transplantation. Each bar represents one individual animal. B) Human thymocyte subsets in thymic grafts 20 weeks after double graft implantation. Human (a) and porcine (b) thymic grafts were harvested from HU/HU and SW/HU mice, respectively. Human CD4 and CD8 cell populations were analyzed using flow cytometry. Similar thymocyte populations were detected in human (c) and porcine (d) thymic grafts of HU+SW dual-grafted mice. One representative result from 2 individual mice of each type is shown.