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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Bone. 2009 Mar 2;44(6):1121–1133. doi: 10.1016/j.bone.2009.02.018

Figure 4.

Figure 4

Defective differentiation of periosteal cells into osteoblasts in Wnt1Cre;Pkd1 mice in response to expansive force. Col1a1 in situ hybridization of frontal sections of midpalatal sutures of control (A-E) and Wnt1Cre;Pkd1 (F-J) animals without expansion (A and F) and with expansion at days 1 (B and G), 3 (C and H), 7 (D and I) and 14 (E and J). (B and C) Increased expression for Col1a1 (green) in the periosteal region. (D) Col1a1-positive cells are distributed in the suture. (J) Col1a1-positive cells are located in the perioteal region. Scale bar (A): 100μm.