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Distribution of mitotic phases in NHMEC HI and LI cells exposed to 0, or 200 μM AZT for 24 hr
| Prophase | Metaphase | Anaphase | Telophase | Total Mitosis(a) | |
|---|---|---|---|---|---|
| HI control | 15.3±1.9 | 4.0±1.0 | 3.5±0.9 | 18.3±2.1 | 41.0±3.1 |
| HI AZT | 24.9±2.5* | 3.7±1.0 | 2.7±0.8 | 18.7±2.1 | 50.0±3.4** |
| LI control | 22.6±2.3 | 5.2±1.1 | 2.5±0.8 | 16.9±2.0 | 47.2±3.3 |
| LI AZT | 21.6±2.3 | 4.2±1.0 | 2.7±0.8 | 15.4±1.9 | 44.0±3.2 |
p= 0.002
p= 0.016
Total cell scored ∼4000/strain/treatment, total mitotic figures scored = 200/strain/treatment
