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. Author manuscript; available in PMC: 2010 May 11.
Published in final edited form as: Vaccine. 2009 Mar 13;27(21):2760–2767. doi: 10.1016/j.vaccine.2009.03.003

Figure 1. Organization of the HSV-1 genome.

Figure 1

A.Diagram of the structure of the HSV genome. The unique sequences are represented as a line, and the repeated sequences are represented as boxes. a= terminal repeats, b, b′ = L component inverted repeats, c, c′= S component inverted repeats; B. Expanded map of the right end of the genome showing the ORFs of the IE genes; C. Expanded map of the right end of the d106 genome showing the deletions (open boxes) of ICP4 and ICP22/47 gene promoters, and the CMV-GFP cassette (open arrow) insertion in the ICP27 gene.