TABLE 2.
Unadjusted ORs for primary placental pathologic condition, according to demographic and medical factors.
| Variable |
P value for test of association between risk factor and placental pathologic condition |
OR | |||
|---|---|---|---|---|---|
| AFIS (95% CI) | Chronic villitis (95% CI) |
Maternal vascular pathologic condition (95% CI) |
Fetal vascular pathologic condition (95% CI) |
||
| Age (y) | .0573 | ||||
| <35 | Reference | Reference | Reference | Reference | |
| ≥35 | 0.46 (0.23, 0.92) | 0.99 (0.67, 1.45) | 1.33 (0.93, 1.91) | 1.25 (0.83, 1.87) | |
| Race | .1093 | ||||
| White (including other) | Reference | Reference | Reference | Reference | |
| African American | 1.59 (1.01, 2.50) | 0.83 (0.57, 1.21) | 1.28 (0.91, 1.81) | 0.82 (0.54, 1.25) | |
| Maternal education | .3637 | ||||
| ≤High school | 1.51 (0.95, 2.41) | 0.84 (0.58, 1.21) | 1.05 (0.73, 1.51) | 0.84 (0.56, 1.28) | |
| Some college | 1.08 (0.64, 1.84) | 0.72 (0.49, 1.07) | 1.43 (1.01, 2.02) | 1.08 (0.72, 1.61) | |
| ≥College | Reference | Reference | Reference | Reference | |
| PIR (%) | .0714 | ||||
| <100 | 1.83 (1.08, 3.08) | 0.56 (0.35, 0.92) | 1.16 (0.78, 1.74) | 0.77 (0.47, 1.26) | |
| 100-199 | 1.39 (0.76, 2.54) | 0.80 (0.50, 1.27) | 0.86 (0.54, 1.37) | 0.68 (0.39, 1.18) | |
| >200 | Reference | Reference | Reference | Reference | |
| Mother’s marital status | .0055 | ||||
| Married | 0.50 (0.33, 0.76) | 1.40 (0.99, 1.99) | 0.79 (0.58, 1.08) | 1.17 (0.81, 1.71) | |
| Single, divorced widowed, separated |
Reference | Reference | Reference | Reference | |
| Body mass index (kg/m2) | .3222 | ||||
| <19.8 | 0.93 (0.51, 1.69) | 0.86 (0.55, 1.34) | 1.28 (0.85, 1.93) | 1.58 (1.01, 2.46) | |
| 19.8-26.0 | Reference | Reference | Reference | Reference | |
| 26.1-29.0 | 0.45 (0.19, 1.07) | 1.15 (0.73, 1.81) | 1.35 (0.87, 2.35) | 1.43 (0.87, 2.35) | |
| >29.0 | 1.08 (0.67, 1.74) | 1.13 (0.80, 1.60) | 1.14 (0.80, 1.62) | 1.27 (0.86, 1.89) | |
| Smoking during pregnancy | 0.0842 | ||||
| No | Reference | Reference | Reference | Reference | |
| Yes | 1.81 (1.04, 3.17) | 0.66 (0.39, 1.13) | 1.35 (0.87, 2.10) | 1.43 (0.88, 2.33) | |
| Previous birth | .1519 | ||||
| None | Reference | Reference | Reference | Reference | |
| ≥1 | 0.67 (0.45, 1.01) | 1.11 (0.82, 1.51) | 0.79 (0.59, 1.06) | 0.95 (0.68, 1.32) | |
| Previous preterm birth | .0128 | ||||
| No | Reference | Reference | Reference | Reference | |
| Yes | 0.46 (0.20, 1.07) | 1.53 (1.01, 2.32) | 1.15 (0.75, 1.78) | 0.59 (0.32, 1.07) | |
| Previous miscarriage | .6872 | ||||
| No | Reference | Reference | Reference | Reference | |
| Yes | 0.71 (0.44, 1.15) | 1.021 (0.74, 1.40) | 1.07 (0.78, 1.46) | 1.08 (0.76, 1.53) | |
| Previous elective termination |
.0313 | ||||
| No | Reference | Reference | Reference | Reference | |
| Yes | 2.19 (1.42, 3.40) | 0.74 (0.50, 1.09) | 0.98 (0.68, 1.42) | 1.14 (0.77, 1.69) | |
| Chronic hypertension | .0109 | ||||
| No | Reference | Reference | Reference | Reference | |
| Yes | 0.31 (0.10, 0.98) | 0.93 (0.55, 1.59) | 1.47 (0.92, 2.36) | 1.95 (1.20, .018) | |
| PIH | .0073 | ||||
| No | Reference | Reference | Reference | Reference | |
| Yes | 0.75 (0.46, 1.22) | 1.13 (0.81, 1.53) | 1.48 (1.10, 2.01) | 1.71 (1.22, 2.40) | |
| Preeclampsia | .0133 | ||||
| No | Reference | Reference | Reference | Reference | |
| Yes | 0.18 (0.03, 1.34) | 1.05 (0.54, 2.06) | 1.83 (1.02, 3.28) | 1.12 (0.54, 2.32) | |
| Prepregnancy diabetes mellitus |
.1097 | ||||
| No | Reference | Reference | Reference | Reference | |
| Yes | Insufficient Data | 1.22 (0.62, 2.41) | 1.10 (0.54, 2.27) | 0.46 (0.20, 1.03) | |
| GDM | .3450 | ||||
| No | Reference | Reference | Reference | Reference | |
| Yes | 0.47 (0.11, 1.96) | 1.53 (0.78, 2.99) | 1.45 (0.74, 2.83) | 0.86 (0.36, 2.07) | |
| Infant’s gender | .2145 | ||||
| Female | Reference | Reference | Reference | Reference | |
| Male | 1.21 (0.81, 1.80) | 0.91 (0.61, 1.07) | 0.97 (0.73, 1.28) | 0.78 (0.57, 1.07) | |