. 2009 Apr 29;8:15. doi: 10.1186/1476-511X-8-15

Table 1.

Gene expression in CD14⁺monocytes following treatment with CLA for 3 days^a

	Cathepsin K	RANK	MMP-9	TNF-α
9cis,11trans CLA (μM)
0	1.00^a	1.00^a	1.00^a	1.00^a
6.25	0.88 ± 0.15^ab	0.72 ± 0.04^ab	1.15 ± 0.17^a	1.08 ± 0.07^a
12.5	0.59 ± 0.08^bc	0.50 ± 0.16^b	0.85 ± 0.16^a	1.14 ± 0.16^a
25	0.44 ± 0.03^c	0.50 ± 0.05^c	1.00 ± 0.07^a	0.99 ± 0.17^a
50	0.43 ± 0.05^c	0.14 ± 0.05^c	0.82 ± 0.10^a	0.91 ± 0.10^a

10trans,12cis CLA (μM)
0	1.00^a	1.00^a	1.00^abc	1.00^abc
6.25	0.80 ± 0.09^a	0.66 ± 0.07^b	1.22 ± 0.06^b	1.19 ± 0.08^abc
12.5	0.55 ± 0.06^b	0.60 ± 0.12^bc	0.88 ± 0.10^c	1.40 ± 0.19^b
25	0.53 ± 0.09^b	0.55 ± 0.09^bc	0.86 ± 0.07^c	0.96 ± 0.09^abc
50	0.47 ± 0.14^b	0.37 ± 0.02^bc	0.66 ± 0.08^c	0.85 ± 0.09^c

^aValues represent the mean ± SEM (n ≥ 3), expressed as relative arbitrary units (R.A.U.) for mRNA expression, determined by real-time RT-PCR. Values with different letters represent significant differences within isomer treatment at P < 0.05.