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. 2009 Apr 17;10(5):459–465. doi: 10.1038/embor.2009.70

Figure 2.

Figure 2

Unique structure of eIF6. The eIF6 protein is highly conserved and has a unique star-like structure known as pentein, which is formed by five quasi-identical α/β-subdomains (A–E) that enclose a cavity filled by 16 ordered water molecules (Groft et al, 2000). Here we show top and side views of the Saccharomyces cerevisiae structure, in which the cavity is closed. The structure of eIF6 is relatively rigid and has no structural homologue. The S. cerevisiae eIF6 Protein Data Bank access code is 1G62. eIF6, eukaryotic initiation factor 6.