Table 5.
Changes in WoLF PSORT localization prediction due to mutations.
| Mutant compartment | ||||||||||||||||||
| Wild type compartmenta | PM | S | S_PM | C | C_N | C_M | N | N/C_N | N/C/ C_N |
ER | ER_ M |
M | M_N | M_N/ C_M |
P | L | CK | Total |
| P | 2/2 | 0/1 | 1/6 | 2/2 | 0/1 | 0/6 | 1/1 | 6/19 | ||||||||||
| S | 0/1 | 0/4 | 0/1 | 4/5 | 1/1 | 4/9 | 0/2 | 9/23 | ||||||||||
| S/S_PM | 0/1 | 0/1 | ||||||||||||||||
| C | 0/6 | 2/3 | 3/9 | 3/3 | 5/6 | 0/1 | 3/6 | 2/2 | 18/36 | |||||||||
| C/C_N | 1/1 | 1/1 | ||||||||||||||||
| C_N | 0/2 | 18/19 | 4/8 | 2/2 | 2/2 | 3/3 | 29/36 | |||||||||||
| C_M | 1/1 | 1/1 | ||||||||||||||||
| N | 0/1 | 0/10 | 6/10 | 7/7 | 2/4 | 15/32 | ||||||||||||
| G/ER_G | 0/1 | 0/1 | ||||||||||||||||
| ER | 0/11 | 0/1 | 1/1 | 0/1 | 2/2 | 3/16 | ||||||||||||
| M | 0/2 | 3/3 | 6/6 | 0/2 | 0/2 | 9/15 | ||||||||||||
| ER_M | 1/1 | 1/1 | ||||||||||||||||
| M/P/M_P | 0/1 | 0/1 | ||||||||||||||||
| Total | 0/21 | 7/21 | 0/1 | 37/53 | 7/11 | 3/3 | 12/20 | 0/3 | 0/1 | 4/7 | 1/1 | 11/28 | 2/2 | 3/3 | 3/3 | 0/3 | 2/2 | 92/183 |
The numbers separated by the slash sign are for how many proteins the wild type localization have been correctly predicted, and the number of analyzed mutations, respectively.
aC, cytosol; CK, cytoskeleton; G, Golgi compartment; M, mitochondrial; N, nuclear; P, peroxisomal; PM, plasma membrane; S, secreted. Slash sign indicates alternative localization predictions and underline sign multiple predicted localizations.