Table 2.
Summary of ORs for various comparisons
| E185Q comparison* |
Population (number of data sets)§ | Fixed-effects OR(95%CI) | Random-effects OR(95%CI) | Heterogeneity (P value Q test) |
P value (fixed) |
P value (random) |
|---|---|---|---|---|---|---|
| (GC+CC) vs GG | 17 | 1.06(1.00–1.12) | 1.06(1.00–1.12) | 0.54 | 0.05 | 0.05 |
| CC vs GG | 16 | 0.99(0.90–1.09) | 0.98(0.85–1.13) | 0.02 | 0.83 | 0.78 |
| CC vs (GC +GG) | 16 | 0.95(0.87–1.04) | 0.94(0.82–1.07) | 0.03 | 0.28 | 0.36 |
| C vs G | 16 | 1.02(0.97–1.08) | 1.02(0.98–1.07) | 0.10 | 0.45 | 0.36 |
*Additive genetic model: CC vs GG, recessive genetic model: CC vs (GC +GG), dominant genetic model: (GC+CC) vs GG
§Ryk's study was not involved in 16 studies.