Figure 5.
Femoral Histology in the Two SRP Type III Patients and in a Control Fetus
Physeal growth zone shows short and irregular columns in the proliferative zone in the family 5 case (A×10, B×20) and in the family 3 case (C×10, D×20), compared to a control of the same gestational age (E×10, F×20). Note also the more severe disorganization in the family 5 case, with associated elongated tongues of hypertrophic cartilage (asterisks) and patchy cellular proliferation.