Table 1.
Top 5 SNPs that Were Individually Associated with Asthma According to Allelic-Model p Values in CAMP/Illumina GWA Study
| SNP | CHR | BP | HWE p Value | Minor Allele | MAF Cases | MAF Controls | Allelic p Value | OR (95% CI) |
|---|---|---|---|---|---|---|---|---|
| rs2548659 | 5 | 59419643 | 0.45 | G | 0.23 | 0.34 | 1.5 × 10−7 | 0.58 (0.48–0.71) |
| rs1588265 | 5 | 59405551 | 0.68 | G | 0.23 | 0.34 | 4.3 × 10−7 | 0.60 (0.49–0.73) |
| rs983280 | 5 | 59480894 | 0.63 | G | 0.23 | 0.34 | 4.8 × 10−7 | 0.60 (0.49–0.73) |
| rs11778371 | 8 | 27375822 | 1 | A | 0.09 | 0.04 | 8.1 × 10−7 | 2.32 (1.65–3.27) |
| rs1544791 | 5 | 59474839 | 0.63 | A | 0.24 | 0.34 | 9.7 × 10−7 | 0.61 (0.54–0.78) |
Minor allele corresponds to Illumina's top-strand convention. CHR: chromosome. BP: base pairs along corresponding chromosome. HWE: Hardy-Weinberg equilibrium. MAF: minor-allele frequency. OR: odds ratio.