Table 5.

Family-Based Analysis of Airway Responsiveness Association to PDE4D SNPs in CAMP and Costa Rica Trios

SNP	Minor Allele	CAMP p Value	Costa Rica p Value
rs1588265	G	0.42	−0.74
rs1544791	A	0.38	−0.74

Association between SNPs and the log-transformed methacholine concentration (in CAMP) and dose (in Costa Rica) that caused a 20% decrease in FEV1 were measured under an additive model, in which adjustments were made for age and gender. No significant associations were found. The negative sign indicates association direction.