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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Nat Genet. 2009 Feb 8;41(3):334–341. doi: 10.1038/ng.327

Figure 2. CDKN2B messenger RNA expression in subcutaneous fat tissue stratified by rs4977574 genotyped on 9p21.3.

Figure 2

The CDKN2B transcript level in each of 848 subcutaneous fat samples was compared with the mean level in a control mRNA pool of 100 randomly-selected samples. A ratio of the sample transcript level over that in control pool was first calculated and then log-transformed. This percent change is shown on the y-axis with the genotype at rs4977574 shown on the x-axis. Note that the G allele represents the risk allele for MI with each copy of the G allele increasing risk for MI by 28%.