Table 1.
Sleep AHEAD participant characteristics at baseline
| Total Sleep AHEAD participants | Sleep AHEAD participants (male) | Sleep AHEAD participants (female) | P | |
|---|---|---|---|---|
| n | 305 | 122 | 183 | |
| Race/ethnicity (%) | <0.0001 | |||
| White | 73.0 | 90.1 | 61.8 | |
| African American | 19.1 | 6.6 | 27.3 | |
| Other | 7.9 | 3.3 | 10.9 | |
| Postmenopause | 90.1 | N/A | 90.1 | n/a |
| Age (years) | 61.3 ± 6.5 | 61.4 ± 7.1 | 61.3 ± 6.1 | 0.89 |
| BMI (kg/m2) | 36.5 ± 5.8 | 36.1 ± 5.6 | 36.7 ± 5.9 | 0.34 |
| Weight (kg) | 101.7 ± 18.0 | 110.9 ± 16.5 | 95.6 ± 16.2 | <0.0001 |
| Height (cm) | 167.0 ± 9.7 | 175.5 ± 7.0 | 161.3 ± 6.6 | <0.0001 |
| Waist circumference (cm) | 115.0 ± 13.0 | 120.9 ± 12.1 | 111.0 ± 12.1 | <0.0001 |
| Neck circumference (cm) | 41.1 ± 4.4 | 44.4 ± 3.2 | 39.0 ± 3.1 | <0.0001 |
| A1C | 7.2 ± 1.1 | 7.4 ± 1.1 | 7.1 ± 1.0 | 0.03 |
| Total sleep time (h) | 6.0 ± 1.2 | 5.8 ± 1.3 | 6.1 ± 1.1 | 0.03 |
| Sleep efficiency (%) | 77.5 ± 11.1 | 77.1 ± 11.8 | 77.7 ± 10.6 | 0.69 |
| Time in non-REM stages (h) | 4.9 ± 1.0 | 4.9 ± 1.1 | 5.0 ± 1.0 | 0.32 |
| Time in REM stages (h) | 1.0 ± 0.5 | 0.9 ± 0.5 | 1.1 ± 0.5 | 0.002 |
| Sleep time supine (h) | 2.1 ± 2.0 | 1.9 ± 1.9 | 2.2 ± 2.1 | 0.21 |
| Obstructive apnea index | 11.1 ± 12.8 | 14.2 ± 15.5 | 9.1 ± 10.2 | 0.008 |
| Central apnea index | 0.4 ± 1.0 | 0.6 ± 1.2 | 0.3 ± 0.7 | 0.003 |
| Hypopneas with ≥4% oxygen desaturation* | ||||
| Apnea-hypopnea index | 20.5 ± 16.8 | 24.6 ± 18.6 | 17.8 ± 15.0 | 0.001 |
| Hypopnea index | 9.0 ± 8.1 | 9.8 ± 8.3 | 8.4 ± 8.0 | 0.16 |
| Oxygen desaturation index (≥4%)† | 17.6 ± 14.7 | 20.0 ± 15.9 | 15.9 ± 13.7 | 0.03 |
| Participants that spent >10% of time below 90% saturation (%) | 16.1 | 20.5 | 13.1 | 0.11 |
| Oxygen saturation nadir | 81.4 ± 8.3 | 81.2 ± 7.5 | 81.6 ± 8.8 | 0.65 |
| Epworth Sleepiness Score | 7.9 ± 4.6 | 8.0 ± 4.5 | 7.8 ± 4.7 | 0.80 |