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. Author manuscript; available in PMC: 2009 May 13.
Published in final edited form as: Cell. 2007 Jun 29;129(7):1401–1414. doi: 10.1016/j.cell.2007.04.040

Figure 5. miRNA expression in cell differentiation experiments.

Figure 5

Cell lines were treated and differentiated into neurons (A) and osteoblasts (B). (C) A thyroid stimulating hormone (TSH)-dependent rat cell line FRTL5 was dedifferentiated by induction of a chimeric RAS protein. Expression profiles for orthologous miRNA precursor clusters with 5% or more relative cloning frequency in at least one sample are depicted in a color-coded manner (see Figure 3 for details). Abbreviations: dcAMP, dibutyryl cAMP; FBS, fetal bovine serum; TPA, trans-phorbol ester; RA, retinoic acid; USSC, human unrestricted somatic stem cell; orth, indicates that the hsa-mir-470 cluster is orthologous to the rodent mir-463 clusters.