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. Author manuscript; available in PMC: 2010 Mar 1.

Published in final edited form as: Mol Cancer Ther. 2009 Feb 24;8(3):615–625. doi: 10.1158/1535-7163.MCT-08-1196

Induction of gene expression by ATRA and/or atrovastatin in NB4 cells. A. Venn diagrams of differentially expressed RefSeqs characterized by an absolute log₂ (fold change) of at least 1. Overlaps of the genes expressed at different time points for ATRA alone (left upper panel); Atrovastatin alone (right upper panel); and ATRA + Atorvastatin (left lower panel) are shown. Differentially expressed RefSeqs characterized by an absolute log₂ (fold change) of at least 1 in at least one of the different time points of treatment is also shown (right lower panel). B-D. Relation found within differentially expressed genes, in at least one of the treatments and present in the enriched functional classes. Cluster 1, centered on IL1B gene at time point 48h (B), cluster 2, centered on MYC gene at time point 48h (C), cluster 3, centered on EGR1 gene at time point 48h (D).

Induction of gene expression by ATRA and/or atrovastatin in NB4 cells. A. Venn diagrams of differentially expressed RefSeqs characterized by an absolute log₂ (fold change) of at least 1. Overlaps of the genes expressed at different time points for ATRA alone (left upper panel); Atrovastatin alone (right upper panel); and ATRA + Atorvastatin (left lower panel) are shown. Differentially expressed RefSeqs characterized by an absolute log₂ (fold change) of at least 1 in at least one of the different time points of treatment is also shown (right lower panel). B-D. Relation found within differentially expressed genes, in at least one of the treatments and present in the enriched functional classes. Cluster 1, centered on IL1B gene at time point 48h (B), cluster 2, centered on MYC gene at time point 48h (C), cluster 3, centered on EGR1 gene at time point 48h (D).