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. Author manuscript; available in PMC: 2010 Mar 1.

Published in final edited form as: Mol Cancer Ther. 2009 Feb 24;8(3):615–625. doi: 10.1158/1535-7163.MCT-08-1196

Expression of genes associated with differentiation in ATRA resistant APL cells. NB4.306 cells were treated for 24 hrs (left panels) or 48 hrs (right panels) with ATRA (0.5μM), atorvastatin (2μM), or the combination of ATRA and atorvastatin, as indicated. Expression of mRNAs for CCL3 (A), IL1B (B), BTG2 (C) or NCF2 (D) was evaluated by quantitative real time RT-PCR (TaqMan), using GAPDH for normalization. Data are expressed as fold increase over untreated samples and represent means ± S.E. of 2-independent experiments.

Expression of genes associated with differentiation in ATRA resistant APL cells. NB4.306 cells were treated for 24 hrs (left panels) or 48 hrs (right panels) with ATRA (0.5μM), atorvastatin (2μM), or the combination of ATRA and atorvastatin, as indicated. Expression of mRNAs for CCL3 (A), IL1B (B), BTG2 (C) or NCF2 (D) was evaluated by quantitative real time RT-PCR (TaqMan), using GAPDH for normalization. Data are expressed as fold increase over untreated samples and represent means ± S.E. of 2-independent experiments.