Table 4.
Minimum inhibitory concentration (MIC) values for selected tetracycline analogs (μg/mL).
| |
SA 100 |
SA 2147 |
SA 757 |
SA 2011 |
EF 708 |
EF 1092 |
SP 1195 |
SP 911 |
EC 102 |
EC 2271 |
EC 119 |
EC 121 |
AB 1630 |
PA 103 |
HI 1224 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Resistance: | M | M, T | M, T | V, T | P, T | T | T | Mult | A, T | ||||||
 |
1 | 0.5 | 64 | 32 | 0.5 | >64 | 0.25 | 64 | 1 | 64 | 2 | 64 | 1 | 32 | 16 |
 |
0.25 | 0.12 | 0.5 | 0.12 | 0.12 | 0.5 | <0.06 | <0.06 | >16 | >16 | >16 | 8 | 0.25 | >16 | 2 |
 |
0.25 | 0.25 | 0.5 | 0.25 | 0.5 | 0.5 | 0.25 | 0.25 | >32 | >32 | ND | ND | 8 | >32 | >32 |
 |
0.25 | 0.25 | 0.5 | 0.25 | 0.25 | 0.5 | 0.25 | 0.25 | >32 | >32 | ND | ND | 2 | >32 | 64 |
 |
1 | 1 | 1 | 0.5 | 0.5 | 0.5 | 0.25 | 0.25 | >32 | >32 | >32 | >32 | 8 | >32 | 0.5 |
 |
1 | 0.5 | 2 | 0.5 | 0.12 | 2 | <0.06 | 0.5 | 0.5 | 1 | 1 | 0.25 | 2 | >32 | 0.06 |
 |
0.5 | 0.25 | 2 | 0.5 | <0.06 | 1 | <0.06 | 0.5 | 0.25 | 1 | 1 | 0.25 | 0.5 | >32 | 0.06 |
 |
0.5 | 0.25 | 1 | 0.25 | <0.06 | 0.5 | <0.06 | 0.5 | 0.5 | 1 | 2 | 0.12 | 1 | 32 | 0.25 |
Organisms in red are antibiotic-resistant. Abbreviations: A, ampicillin; M, methicillin; P, penicillin; V, vancomycin; T, tetracycline; Mult, multiple. Organisms: SA, S. aureus; EF, E. faecium; SP, S. Pneumoniae; EC, E. coli; AB, A. baumanii; PA, P. aeruginosa; HI, H. influenzae.