Table 2.
Associations of CASR with BP in longitudinal study (P values)
| SNP | Position | NT | HWE (P value) | MAF | Population-based analysis (n = 223)
|
Family-based analysis (n = 123 families)
|
||
|---|---|---|---|---|---|---|---|---|
| SBP | DBP | SBP | DBP | |||||
| rs6776158 | Promoter | A/G | 0.62 | 0.42 | 0.91 | 0.13 | 0.41 | 0.02 |
| rs1501900 | Intron 1 | A/T | 0.70 | 0.08 | 0.90 | 0.31 | 0.90 | 0.36 |
| Rs937627 | Intron 1 | G/T | 0.07 | 0.10 | 0.13 | 0.32 | 0.89 | 0.64 |
| rs6438712 | Intron 1 | A/G | 0.96 | 0.29 | 0.004A | 0.16 | 0.11 | 0.005A |
| rs4678172 | Intron 1 | G/T | 0.51 | 0.30 | 0.004T | 0.11 | 0.006T | 0.006T |
| rs9874845 | Intron 1 | A/T | 0.88 | 0.34 | 0.019A | 0.13 | 0.04 | 0.01 |
| rs4678059 | Intron 1 | A/T | 1.00 | 0.14 | 0.45 | 0.47 | 0.81 | 0.24 |
| rs1965357 | Intron 1 | C/T | 0.51 | 0.18 | 0.68 | 0.21 | 0.04 | 0.02 |
| rs937626 | Intron 1 | A/G | 0.95 | 0.35 | 0.003A | 0.16 | 0.04 | 0.01 |
| rs3749204 | Intron 3 | A/T | 0.54 | 0.42 | 0.55 | 0.19 | 0.02 | 0.21 |
| rs3749207 | Intron 3 | C/T | 0.30 | 0.31 | 0.19 | 0.77 | 0.75 | 0.40 |
| rs3804593 | Intron 4 | A/G | 0.98 | 0.26 | 0.98 | 0.38 | 0.07 | 0.06 |
| rs2279802 | Intron 5 | A/G | 0.33 | 0.06 | 0.62 | 0.69 | 0.82 | 0.59 |
| rs2270916 | Intron 6 | C/T | 1.00 | 0.06 | 0.32 | 0.30 | 0.20 | 0.94 |
| rs9740 | 3′-UTR | A/G | 0.49 | 0.17 | 0.42 | 0.82 | 0.81 | 0.86 |
The chromosomal position was obtained from build 36.2. Letters in superscript depict the nucleotides that are associated with a higher BP (A, Adenine; T, thymine). HWE, Hardy-Weinberg equilibrium; MAF, minor allele frequency; NT, nucleotide; UTR, untranslated region.