Table 2. Summary of Preferential Interaction Coefficients for BSA as Measured by VPO^a and Comparison to Literature Values.

cosolute	Ω3	Γμ1	Γμ3b	Γμ1,μ3	Γμ1,μ3Lit
argHCl	(1.713 ± 0.003) - (0.611 ± 0.006)m3	(-1.64 ± 0.6) + (1.7 ± 3.9)m3 - (13.3 ± 5.4)m32	(1.72 ± 0.96)[3] - (23.2 ± 4.0) [3]2	(1.43 ± 0.96)[3] - (22.8 ± 4.0) [3]2	(12.6 ± 4.5)[3] - (22.0 ± 5.3)[3]2 c
gdnHCl	(1.755 ± 0.001) - (0.576 ± 0.005)m3	(-1.8 ± 0.4) + (11.2 ± 1)m3	(12.4 ± 1)[3]	(12.3 ± 1)[3]	(13.0 ± 1.2)[3]d
glucose	(1.055 ± 0.001) - (0.004 ± 0.002)m3	(-1.4 ± 0.6) - (17.8 ± 0.8)m3	(-20.6 ± 0.4)[3]	(-20.8 ± 0.4)[3]	(-19.8 ± 0.9)[3]e
glycerol	(1.014 ± 0.001) - (0.0012 ± 0.001)m3	(-4.1 ± 0.8) - (12.3 ± 1.2)m3	(-14.0 ± 0.4)[3]	(-14.3 ± 0.4)[3]	(-12 ± 4)[3]f
urea	(0.963 ± 0.002) - (0.092 ± 0.002)m3	(-5.0 ± 0.4) + (6.2 ± 0.6)m3	(6.4 ± 0.4)[3]	( 6.2 ± 0.4)[3]	(6 ± 2)[3]g

It should be noted that [3] represents the molar concentration of the cosolute.

^aThe base buffer was 40 mM Na-Phosphate, pH 6.0 and BSA concentration held constant at 1.8 mM.

^bThe values represented are an average of the separate approximations computed by eqs 15 and 18.

^cCalculated from data in Reference ³⁷.

^dCalculated from data in Reference ³⁰.

^eCalculated from data in Reference ²⁹.

^fCalculated from data in Reference ⁴¹.

^gCalculated from data in Reference ³⁶.