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. Author manuscript; available in PMC: 2010 Feb 19.
Published in final edited form as: J Phys Chem B. 2009 Feb 19;113(7):2050–2058. doi: 10.1021/jp808042w

Table 3. Summary of Preferential Interaction Coefficients for Lysozyme as Measured by VPOa and Comparison to Literature Values.

cosolute Ω3 Γμ1 Γμ3b Γμ1,μ3 Γμ1,μ3Lit
argHCl (1.670 ± 0.001) - (0.560 ± 0.004)m3 (-1.9 ± 0.3) + (5.2 ± 2.2)m3 - (6.5 ± 3.3)m32 (5.8 ± 0.4)[3] - (10.8 ± 1.4)[3]2 (5.5 ± 0.4)[3] - (10.6 ± 1.4)[3]2 (-3.6 ± 1.6) + (8.0 ± 9)[3] - (9.2 ± 11.3)[3]2 c
gdnHCl (1.770 ± 0.001) - (0.584 ± 0.002)m3 (-2.0 ± 0.3) + (2.9 ± 0.6)m3 (3.7 ± 1)[3] (3.6 ± 1)[3] N/A
glucose (1.026 ± 0.001) - (0.001 ± 0.002)m3 (-2.8 ± 0.3) - (2.4 ± 0.5)m3 (-2.74 ± 0.3)[3] (-3.07 ± 0.3)[3] N/A
glycerol (1.018 ± 0.001) - (0.002 ± 0.002)m3 (-2.2 ± 0.3) - (5.7 ± 0.5)m3 (-6.3 ± 0.3)[3] (-6.5 ± 0.3)[3] N/A
urea (0.962 ± 0.001) - (0.090 ± 0.002)m3 (-4.3 ± 0.3) + (2.7 ± 0.3)m3 (3.4 ± 1)[3] (3.2 ± 1)[3] (6 ± 1)[3] d

It should be noted that [3] represents the molar concentration of the cosolute.

a

The base buffer was 40 mM Na-Phosphate, pH 6.0 and lysozyme concentration held constant at 3.5 mM.

b

The values represented are an average of the separate approximations computed by eqs 15 and 18.

c

Calculated from data in Reference 37.

d

Calculated from data in Reference 31.