Table 5. Preferential Interaction Coefficients for Proteins in Arginine HCl Solutionsa as Determined by Dialysis/Densimetry Measurements.
[arginine] (M) | ϕ2 o (mL/g) | ϕ2’o (mL/g) | Γμ 1μ3 |
---|---|---|---|
BSA, pH 6.0 | |||
0.47 | 0.708 ± 0.002 | 0.713 ± 0.001 | (-5.2 ± 2.8) |
0.87 | 0.717 ± 0.002 | 0.734 ± 0.002 | (-21.3 ± 4.3) |
lysozyme, pH 6.0 | |||
0.38 | 0.713 ± 0.002 | 0.706 ± 0.002 | (1.6 ± 0.7) |
0.87 | 0.697 ± 0.002 | 0.710 ± 0.002 | (-3.4 ± 0.8) |
The base buffer was 40 mM sodium phosphate, pH 6.0.