Table 2.
6-Wk Intervention |
12-Wk Intervention
|
|||||||
---|---|---|---|---|---|---|---|---|
HFSED | HFEX | LFSED | LFEX | HFSED | HFEX | LFSED | LFEX | |
n | 14 | 13 | 13 | 15 | 13 | 13 | 14 | 14 |
Initial BW, g | 25.8±0.4 | 24.8±0.4 | 25.5±0.4 | 25.0±0.5 | 24.7±0.7 | 24.8±0.6 | 25.0±0.8 | 25.0±0.7 |
Final BW, g | 32.1±0.9a | 28.2±0.7b | 26.9±0.3b,c | 24.9±0.4c | 38.5±1.2a* | 34.0±1.2b* | 30.7±0.8b,c* | 29.4±0.6c* |
Epididymal fat weight, g | 1.8±0.2a | 1.0±0.1b | 0.7±0.03b,c | 0.5±0.03c | 2.1±0.08a* | 1.5±0.2b* | 1.1±0.1b* | 0.6±0.05c |
REA, % | 5.4±0.3a | 3.6±0.4b | 2.6±0.1b,c | 2.1±0.1c | 5.6±0.2a* | 4.3±0.4b | 3.6±0.2b* | 2.0±0.1c |
Heart weight/BW | 0.65±0.08 | 0.84±0.2 | 0.65±0.05 | 0.75±0.07 | 0.40±0.04* | 0.51±0.05 | 0.54±0.04 | 0.60±0.06 |
Cumulative caloric intake, kcal | 512±16a | 474±12a,b | 455±14b | 426±8b | 1,039±23a* | 994±20a,b* | 916±18c* | 936±13b,c* |
Values are means ± SE. HFSED, HFD, sedentary; HFEX, HFD, exercised; LFSED, 10% fat diet (LFD), no sedentary; LFEX, LFD, exercise; n, no. of animals; BW, body weight; REA, epididymal fat pad weight/BW. Different letters represent significant between-group differences within time point based on ANOVA with post hoc Tukey's test.
Significant duration effect within group.