Fig. 5.

Effects of eucaloric high-fat feeding (pair-feeding) on body composition, and glucose tolerance. The food intake of the pair-fed group was calorically matched to that of the low-fat diet fed group and the high-fat group consumed significantly more calories than both the low-fat and pair-fed groups (A; P < 0.01). Fat mass gain (B) and body adiposity (C) were elevated in pair-fed animals to nearly the level of ad libitum high-fat fed animals. Likewise, pair-fed animals had similar blood glucose excursion (D) and AUC (E) during an intraperitoneal glucose tolerance test as ad libitum high-fat fed animals. ^#P < 0.05; *P < 0.01. C: symbols below low-fat data points indicate statistical significance compared with pair-fed group and symbols above high-fat data points indicate statistical significance compared with low-fat group.