Fig. 1.

Tension development. Paired epitrochlearis muscles, incubated with 50 μM N-benzyl-p-toluenesulfonamide (BTS) or vehicle, were electrically stimulated to contract (pulse duration of 0.1 ms, pulse rate of 100 pulses/s, train duration of 10 s, train rate of 2 min⁻¹ for 5 min). A: peak developed tension determined for each tetanus was normalized to the muscle wet weight (g). B: area under the force production curve summed for all 10 tetani was calculated by subtracting the baseline tension from total area under the curve. Values are means ± SE (n = 44). *P < 0.0001, BTS vs. vehicle.