Table 1.
Summary statistics of oxyhemoglobin saturation under conditions of intermittent hypoxia and normoxia by experimental segment
| Parameter | Before IVGTT (0–5 h) |
During IVGTT (5–8 h) | Experimental Duration (0–8 h) | |||
|---|---|---|---|---|---|---|
| Normoxia | Intermittent hypoxia | Normoxia | Intermittent hypoxia | Normoxia | Intermittent hypoxia | |
| Exposure time, min | 297.8 (3.6) | 308.2 (4.6)* | 182.3 (1.8) | 182.2 (1.0) | 480.0 (2.5) | 486.3 (2.2) |
| Event frequency, no./h | 0.0 (0.0) | 24.3 (0.9)* | 0.0 (0.0) | 24.0 (1.0)* | 0.0 (0.0)* | 24.3 (0.8)* |
| SpO2, % | ||||||
| Average | 97.1 (0.2) | 90.6 (0.1)* | 97.1 (0.2) | 91.3 (0.2)* | 97.1 (0.2) | 90.9 (0.1)* |
| Maximum | 98.0 (0.0) | 98.0 (0.0)* | 98.0 (0.0) | 98.0 (0.0)* | 98.0 (0.0) | 98.0 (0.0)* |
| Minimum | 91.5 (1.1) | 75.4 (0.9)* | 93.1 (0.5) | 77.2 (0.9)* | 91.2 (1.1) | 74.8 (0.9)* |
| Time SpO2 <90%, min | 0.1 (0.0) | 114.9 (3.5)* | 0.00 (0.0) | 63.5 (2.6)* | 0.1 (0.1) | 178.3 (5.4)* |
| Time SpO2 <85%, min | 0.0 (0.0) | 47.0 (3.5)* | 0.00 (0.0) | 21.2 (3.2)* | 0.0 (0.0) | 68.3 (6.0)* |
| Time SpO2 <80%, min | 0.0 (0.0) | 9.6 (2.4)* | 0.00 (0.0) | 4.6 (1.4)* | 0.0 (0.0) | 14.2 (3.2)* |
Values are means (SE). IVGTT, intravenous glucose tolerance test; SpO2, oxyhemoglobin saturation.
*
P < 0.0001 comparing the intermittent hypoxia and normoxia condition.