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Overexpression of myocardin in FPVSMC reverses hypoxia-induced SMC phenotype modulation. Cells were transiently transfected with FLAG-tagged myocardin construct or control vector. Transfected cells were treated with hypoxia or normoxia for 24 h. A: representative Western blots. B: quantification of Western blots by densitometry. Data are expressed as means ± SE of 3 independent experiments. *P < 0.05 compared with the cells transfected with control vector (expressed as 100%).
