Fig. 3.

A: effect of the soluble guanylate cyclase inhibitor LY-83583 (LY) on the effect of Arg on net O₂⁻ production by thick ascending limbs in the absence and presence of luminal flow. B: effect of LY on Arg's effect on flow-stimulated net O₂⁻ production. *P < 0.01; n = 5 vs. Arg alone. C: effect of Arg in the presence of LY on net O₂⁻ production by thick ascending limbs in the absence and presence of luminal flow. D: effect of Arg on the flow-induced change in net O₂⁻ production in the presence of LY. *P < 0.006; n = 5 vs. LY alone. Tubules were perfused at 20 nl/min.