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A: effect of Arg in the presence of the phosphodiesterase II inhibitor BAY 60–7550 (BAY) on net O2− production by thick ascending limbs in the absence and presence of luminal flow. B: effect of Arg in the presence of BAY on flow-induced change in net O2− production by thick ascending limbs. P > 0.05; n = 5 vs. Arg alone. Tubules were perfused at 20 nl/min.
