TABLE 2.
Relative mRNA expression levels of SR-BI and CETP in different organs isolated from WT mice, SR-BI KO mice, and SR-BI KO mice expressing human CETP (SR-BI KO/CETP Tg)
| Liver |
Spleen |
Adrenal |
White Adipose Tissue |
|||||
|---|---|---|---|---|---|---|---|---|
| SR-BI | CETP | SR-BI | CETP | SR-BI | CETP | SR-BI | CETP | |
| WT | 0.12 ± 0.02 | n.d. | 0.018 ± 0.001 | n.d. | 0.42 ± 0.12 | n.d. | 0.029 ± 0.015 | n.d. |
| SR-BI KO | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. |
| SR-BI KO/CETP Tg | n.d. | 0.14 ± 0.13 | n.d. | 0.10 ± 0.03 | n.d. | 0.012 ± 0.002 | n.d. | 0.025 ± 0.004 |
Values are relative to the housekeeping gene expression and represent means ± SEM of three mice per group. n.d., not detectable.